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The Unmet Need in PROC
Glucocorticoid Receptor Activation and Chemotherapy Resistance
The Impact of Platinum-Resistance in Ovarian Cancer
Community Support
Expand your knowledge
Dive deeper into platinum-resistant ovarian cancer and glucocorticoid
receptor signaling.
GR Quick
Reference
glucocorticoid system, ovarian cancer, and resistance.
Download the guide
Select
publications
relevant to platinum-resistant
ovarian cancer management.
Read pubs
Visit the National
Comprehensive
Cancer
Network® (NCCN®)
platinum resistance.
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®)
This information is provided solely as a resource for healthcare professionals and may include product uses not approved by the FDA.
Select publications
View key publications about platinum-resistant ovarian cancer.
Melhem A, et al. Clin Cancer Res. 2009.
Administration of glucocorticoids to ovarian cancer patients is associated with expression of the anti-apoptotic genes SGK1 and MKP1/DUSP1 in ovarian tissues.
Read publication
Block TS, et al. Cancer Manag Res. 2017.
Glucocorticoid receptor expression in 20 solid tumor types using immunohistochemistry assay
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Mikosz C, et al. J Biol Chem. 2001.
Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, SGK1.
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Healthcare provider support
Corcept Therapeutics is not affiliated with these organizations but may have provided funding for some
of their educational programs.
GR, glucocorticoid receptor; PROC, platinum-resistant ovarian cancer.
